[한의학][부인과][논문리뷰] Adverse effects of excessive ovarian response on the pregnancy rate of in vitro fertilization treatment

of letrozole versus clomiphene citrate combined with gonadotropins in intrauterine insemination cycles: a pilot study. Fertil Steril 2006; 85: 1774-7.2.보조생식술1) 인공수정(artificial insemination; AI)A치료 방법을 막론하고 효과가 있는 것으로 증명된 치료법. 질환의 완치 혹은완화를 위해 반드시 필요한 치료법. 가이드라인, systemic 리뷰 등 확실한 근거를 가지고 있는 치료법. 한의학의 경우 한의학 논문 혹은 출판된 책에 근거가 있는 것. 정자를 인공적으로 여성의 생식기 내로 주입해

of the individuals own proteins. It is derived from the Greek auto which means self, anti which means against and body. Many autoimmune diseases, notably lupus erythematosus, are caused by such autoantibodies.1. ProductionProteins are produced in a process of evolution that is still a subject of scientific research. Briefly, antibodies are produced by B cells in two ways: (i) randomly, and (ii) in response to a foreign protein or substance within the body. Initially, one B cell produces one specific kind of antibody. In either case, the B cell is allowed to proliferate or is kill

of half embryos of flogMendelian Eramendelism made possible a new precision in thought, and soon the modern concepts of genetics were formulated.Boveris work established more precisely the role of chromosomes in development.his experiments utilized sea urchin embryos with variable number of chromosomes(a condition that today is called aneuploidy). this abnormal situation can be produced when sea urchin eggs are fertilized by two sperm. the frequency of the dispermy in increased by adding an excess number of sperm when fertilizing sea urchin eggs in vitro. the two sperm nuclei and the egg

In PCOS, the ovaries are more sensitive to gonadotropic stimulation, possibly as a result of cytochrome P-450c17 dysregulation- Treatment with a GnRH agonist effectively suppresses serum T and AD- Androgen suppression by GnRH agonist requires larger doses of GnRH agonist than estrogen suppression, high intraovarian androgen은 follicular maturation을 방해하게 되어, theca는 hyperactive하지만,granulosa는 inactive한 상태가 되어 , areomatization이 거의 일어나지 않음Cf. 강의록Hyperfunction of LH-theca cell axis -> excessive production of androgen(T>200ng/d1)Hypo

Ambiguous Genitalia< DIFFERENTIAL DIAGNOSIS & EVALUATION >HISTORY & PHYSICAL EXAMINATIONfamily historymother’s drug history during pregnancymother’s virilizing signhelpful findings on physical examinationpalpable gonad in the labioscrotal fold or scrotum: rule out female pseudohermaphroditismhyperpigmentation of the areola and labioscrotal folds: common in congenital adrenal hyperplasiapalpation of the uterus evidence of dehydration and failure to thriveexistence of other associated congenital anomaliesthe size of the phallus, the location of the urethral meatusCHROMOSOMAL