[약물학] 논문연구-Induction of COX-2 expression by Helicobacter pylori is mediated....

연구가 활발히 진행되고 있다. 1.2.1. mTOR(mammalian target of rapamycin)mTOR pathwaymTOR는 FK506 binding protein 12-rapamycin associated protein 1 (FRAP1) 단백질로 FRAP1 유전자에 의해 발현된다. Moore PA, Rosen CA, Carter KC (April 1996). Assignment of the human FKBP12-rapamycin-associated protein (FRAP) gene to chromosome 1p36 by fluorescence in situ hybridization. Genomics 33 (2): 331–2. doi:10.1006/geno.1996.0206. PMID 8660990. mTOR는 serine/threonine protein kinase로 인슐린, 성장인자, mitogen 등의 신호를 통합하여 세포성장, 세포증

of the spatial regulation by enhancers. The most common and basic enhancer traps are: P lacZ from the bacterium E. coli and P GAL4 from yeast.The enhancer trap also uses some sort of visible marker that allows the new insertions to be recognized such as the white gene, resulting in a red eye color in Drosophila or ampicillin resistance for E. coli.There exists a large number of fly stocks containing GAL4 insertions and an equally large number of fly stocks containing an UAS DNA sequence followed by a gene of interest. The beauty of this arrangement is that the expression of a large nu

is an antibody (a type of protein) manufactured by the immune system that is directed against one or more of the individuals own proteins. It is derived from the Greek auto which means self, anti which means against and body. Many autoimmune diseases, notably lupus erythematosus, are caused by such autoantibodies.1. ProductionProteins are produced in a process of evolution that is still a subject of scientific research. Briefly, antibodies are produced by B cells in two ways: (i) randomly, and (ii) in response to a foreign protein or substance within the body. Initially, one B ce

is that the quasi-relative poverty measure recommended by the NAS panel is the single most informative measure because of its theoretical attributes and its empirical performance thus far, although clearly more research on its empirical performance over time is necessary.그러나, 저자의 견해는 앞으로 경험적 성과에 대한 더 많은 연구가 필요함에도 불구하고 NAS 패널에 의해 추천받은 유사(준) 상대빈곤 척도가 유사(준) 상대빈곤 척도의 이론적 특성과 경험적 성과 때문에 가장 유익한 단일 척도라고 생각한다. Keywo

of COX-1 and retained intron 1, has been shown to possess cyclooxygenase activity in dogs. However, on the basis of nucleotide sequence data obtained in humans, the existence of COX-3 has been called to question by at least two independent research groups.COX-1 and COX-2 are membrane-associated enzymes with a molecular weight of 71 kDa and an amino-acid sequence similarity of 63%. The COX-2 gene is a small immediate early gene(8.3 kb), whereas COX-1 originates from a much larger (22kb) gene. The identification of two isoforms of COX in the early 1990s offered the simple and attractive hypot