Hybrid scaffold for skin regeneration(영문)

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  • 2010.07.20 / 2019.12.24
  • 28페이지 / fileicon pptx (파워포인트 2007이상)
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목차
1.Skin
2.Structure of skin
3.Skin injuries and damages
4.Skin graft
5.Artificial Skin graft
6.Tissue engineering
7.Hybrid scaffold
8.Electrospinning
9.PLGA
10.Hydrogel
본문내용
Protect underlying tissues from injury: mechanical, heat, cold, biological
Prevent excess water loss
Act as a temperature regulator
Serve as a reservoir for food and water: adipose tissue
Serve as a sense organ for cutaneous senses: pain, heat, cold, pressure, touch
Prevent entrance of foreign bodies: microorganisms.
Epidermis
Keratinocytes, melanocytes
About 0.2mm thickness
Provide vital barrier function
Maintain homeostasis
by constant recycling of the basal cell layer

Dermis
Fibroblasts
Constitutes the bulk of the skin
Composed of collagen with elastin
and glycosaminoglycans (GAG’s)
major role in the biomechanics of the skin
Hypodermis
Adipose tissue (vascularized, connective tissue)
Contributes to both the thermoregulatory
Shook absorber and insulator.
Contains larger blood vessels and nerves than those found in the dermis
Burn
2nd degree
Damage in epidermis and partial dermis
Full thickness defect in dermis
Need skin graft
3rd degree
Damage in epidermis, dermis, hypodermis
Need skin graft
Ulcer
breakdown of the skin caused by fluid build-up in the skin from poor vein function (venous insufficiency).
Fluid leaks from the veins into skin tissue when the blood backs up rather than returning to the heart through the veins.
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